Reaction mode of catalytic styrene oxidation using a bis-semicarbazide hexaazamacrocyclic Cu complex
Department of Physical Chemistry, Faculty of Chemical and Food Technology STU, Radlinskeho 9, SK-81237 Bratislava, Slovakia
E-mail: * martin.breza@stuba.sk
Abstract: Catalytic styrene Ph-CH=CH2 oxidation is assumed to be a simple reaction procedure; however, its details require further systematic research. Using quantum-chemical treatment, relevant intermediates have been investigated in various charge and spin states of alternative reaction pathways of styrene oxidation by hydroperoxyl using the [CuL]- catalyst, where H2L = trans-2,9-dibutyl-7,14-dimethyl-5,12-di(4-methoxyphenyl)-1,2,4,8,9,11-hexaazacyclotetradeca-7,14-diene-3,10-dione. Within reaction pathway A, the neutral hydroperoxyl radical is bonded to Cu to form 2[CuL(OOH)]-. Subsequent addition of neutral styrene results in the formation of 2{[CuL(OH)](Ph-CH2-CHO)}-. Reaction pathway B starts with the initial non-radical formation of the π-complex 1[CuL(Ph-CH=CH2)]- which is problematic due to its endothermic character. Subsequent addition of a hydroperoxyl radical leads to 2{CuL[Ph-CH(OOH)-CH2]}- and its oxidation leads to the separation of Ph-CH(OOH)-CH2. The exothermic reaction path A is preferred over the endothermic reaction path B.
Keywords: B3LYP hybrid functional; broken symmetry treatment; Cu oxidation state; electronic structure; geometry optimization
Acta Chimica Slovaca, Vol. 18, No. 1, 2025, pp. 91—107, DOI: 10.2478/acs-2025-0010