Theoretical investigation of aniline derivatives: Correlation of theoretical reaction Gibbs free energies with experimental oxidation potentials
Andrea Kováčová *, Martin Michalík
Institute of Physical Chemistry and Chemical Physics, Slovak University of Technology in Bratislava, Radlinského 9, SK–812 37 Bratislava, Slovakia
E-mail: * andrea.kovacova@stuba.sk
Abstract: Anilines and their derivatives are used in industrial production of dyes, pharmaceuticals, plastics, and synthetic antioxidants. Abstraction of electron and formation of a cation radical represent a significant step in the reactivity of this group of substances. The aim of this study was to theoretically investigate the effect of a substituent on the oxidative electrochemical potential of 64 species of aniline derivatives. Quantum- chemical calculations were performed using the composite G4 method. The obtained linear dependences for reaction Gibbs free energies were correlated with the Hammett constants and available experimental values.
Keywords: anilines, electrochemical potential, reaction Gibbs energies, Gn approach, thermodynamics, implicit solvent model
Acta Chimica Slovaca, Vol. 17, No. 1, 2024, pp. 74—82, DOI: 10.2478/acs-2024-0010