Acta Chimica Slovaca (ACS) publishes papers on fundamental and applied aspects of chemistry, biochemistry, chemical technology, chemical engineering and process control, biotechnology and food technology. Welcome are also topics which include chemical aspects of materials, physical chemistry and chemical physics, analytical chemistry, macromolecular chemistry and biomedical engineering.

Voltammetric determination of Nordiazepam at meniscus modified silver solid amalgam electrode

Petr Samiec *, Zuzana Navrátilová

Department of Chemistry, Faculty of Science, University of Ostrava, 30. dubna 22, 701 03 Ostrava, Czech Republic

E-mail: * p13171@student.osu.cz

Abstract: New electrochemical method for determination of Nordiazepam (NDZ) at meniscus modified silver solid amalgam electrode (m-AgSAE) was developed utilizing differential pulse voltammetry (DPV). The pH effect on the current response of NDZ was studied in the mixture of Britton-Robinson buffer (BR) and methanol (9:1) with optimum pH value of 10. The calibration dependences were examined under the optimal conditions and linearity in the range from 2x10−6 to 1x10−4 mol L−1 with limit of quantification of 1.7x10−6 mol  L−1 were accomplished.

Keywords: meniscus modified silver solid amalgam electrode, differential pulse voltammetry, Nordiazepam

Full paper in Portable Document Format: acs_0194.pdf

Acta Chimica Slovaca, Vol. 7, No. 2, 2014, pp. 105—108, DOI: 10.2478/acs-2014-0018