Preparation, characterization and in vitro bioactivity of polyvinyl alcohol-hydroxyapatite biphasique membranes
Zuzana Balgová *, Martin Palou, Jaromír Wasserbauer, Gabriela Lutišanová a, Jana Kozánková b
Faculty of Chemistry, Brno University of Technology, Purkyňova 464/118, Brno 612 00
a Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava,
Radlinského 9, 812 37 Bratislava, Slovakia
b Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava,
Radlinského 9, 812 37 Bratislava, Slovakia
E-mail: * balgova@fch.vutbr.cz
Abstract: Six membranes of polyvinyl alcohol (PVA) with various weight percent – 0 %, 10 %, 20 %, 30 %, 40 % and 50 % of hydroxyapatite (HA) were prepared. Fourier Transform Infrared (FTIR) spectroscopy was used to identify the different functional groups in membrane composites. The surface morphology was examined through scanning electron microscope JEOL JSM-7600F. The in vitro bioactivity tests in Simulated Blood Fluid (SBF) have been performed up to 28 days, especially for membrane containing 50 wt. % HA. SEM – TESLA BS 300 was used to characterize surface microstructure of biocomposite membranes before and after immersion in SBF. It was observed the formation of clusters within membranes with increasing amount of HA particles due to hydrogen bond and also the agglomeration and crystal growth of HA particles during drying of membranes. The bioactivity was found increasing with time immersion of biocomposite materials in SBF solution.
Keywords: polyvinylalcohol, nanohydroxyapatite, bioactivity, simulated body fluid
Full paper in Portable Document Format: acs_0137.pdf
Acta Chimica Slovaca, Vol. 6, No. 1, 2013, pp. 8—14, DOI: 10.2478/acs-2013-0002