Synthesis and antifungal efficacy of 1,3,5-triazines
Viktor Milata *, Ladislav Reinprecht † a, Juraj Kizlink ‡ b
Faculty of Chemical and Food Technology, STU Bratislava,
Radlinského 9, 812 37 Bratislava, Slovakia
a Faculty of Wood Sciences and Technology, Technical University of Zvolen, T. G. Masaryka 24, SK-960 53 Zvolen, Slovakia
b Faculty of Chemistry, Brno University of Technology Purkyňova 118, CZ-612 00 Brno, Czech Republic
E-mail: * viktor.milata@stuba.sk, † reinpret@vsld.tuzvo.sk, ‡ kizlink@fch.vutbr.cz
Abstract: 1,3,5-triazines with tree identical groups: benzotriazol-1/2-yl, imidazol-1-yl, pyrazolyl-1-yl, 3,5-dimethylpyrazolyl-1-yl, 4,5-diphenylimidazol-1-yl, benzimidazolyl-1-yl, 2-methylbenzimidazolyl-1-yl, or 2-phenylbenzimidazolyl-1-yl were synthesised. Their biological activity against wood-destroying fungi Serpula lacrymans, Coniophora puteana and Trametes versicolor was tested by the impregnated filter paper method. S. lacrymans occurred as the most sensitive fungus (from the 3 fungi) in the presence of triazines. Triazines having three imidazol or three 4,5-diphenylimidazol groups were a slightly more effective than others. However, their efficacy in comparison with the commercial fungicides Tebuconazole and IPBC was insufficient.
Keywords: 1,3,5-triazines, synthesis, wood-destroying fungi, screening test, growth inhibition
Full paper in Portable Document Format: acs_0115.pdf
Acta Chimica Slovaca, Vol. 5, No. 1, 2012, pp. 95—99